You are expected to evaluate/examine (AO3) the significance of different barriers to economic growth and/or economic development (SL+HL)
All the economic and political/social barriers listed earlier, as well as the poverty cycle, create difficulties for creating economic growth and/or economic development in countries. So how do we find the significance of the different barriers? Well, it depends. For example:
In the Democratic Republic of the Congo, the main barriers are political/social. They have immense deposits of valuable resources, but lack proper governance (contrary to its name, it is not a very democratic republic).
In Costa Rica, the main barriers are economic. They have a very stable political system (one of the least corrupt and most democratic in the world), but lack natural resources and rely on agriculture.
The significance varies depending on context, and you will have to evaluate and compare & contrast them depending on the example.